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  • New Launched: Anti human HNF4 alpha mouse monoclonal antibody (clone#H1415)

New Launched: Anti human HNF4 alpha mouse monoclonal antibody (clone#H1415)

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NEW!!       Anti human HNF4 alpha mouse monoclonal antibody (ProteinA purified)   



                            clone# H1415, class G2a, 1mg/mL (100 uL)          cat# PP-H1415-0C


Description

Hepatocyte nuclear factor 4 alpha (HNF4, HNF4a; NR2A1) is a member of orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.

Specificity

This antibody specifically recognizes human HNF4 alpha 1, 2, 4, 5, 7 ,8 and cross reacts with mouse and rat HNF4 alpha 1, 2, 4, 5, 7 ,8.


Application / Recommended Concentration*



*In order to obtain the best results, optimal working dilutions should be determined by each individual user.


WB
1 ug/mL


ELISA
0.3 ug/mL


Supershift Assay
2ng/assay


IHC
10-20 ug/mL


Reference

Tanaka T,et al. J Pathol. 2006; 208(5): 662-72


Sugai M, et al. Pathol Int. 2008; 58(11): 681-6


Manufacturer
Perseus Proteomics Inc.    MADE IN JAPAN


Note
 


 


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Contact
Research Reagents Department / Diagnostics and Reagents Section
TEL:03-5510-2652